Map4k4

Phosphorylates smad1 on thr 322. Map4k4 mitogen activated protein kinase kinase kinase kinase 4 hepatocyte progenitor kinase like germinal center kinase like kinase hgk nck interacting kinase nik is a serine threonine protein kinase related to s.

Silencing Of Map4k4 By Short Hairpin Rna Suppresses Proliferation

Appears to act upstream of the jun n terminal pathway.

Map4k4

. Cerevisiae sterile 20 ste20. Mapk family is a conserved serine threonine protein kinase system and plays a very important role in the process of extracellular signal delivering to cytoplasm. Mitogen activated protein kinase kinase kinase kinase 4 map4k4 also known as hepatocyte progenitor kinase like germinal center kinase like kinase hgk and nck interacting kinase nik is an enzyme specifically a serine threonine s t kinase encoded by the map4k4 gene in humans. Map4k4 is abbreviation of mapk kinase isoform 4 belongs to the mitogen activated protein kinase mapk family.

Map4k4 also known as hgk hematopoietic progenitor kinase germinal center kinase like kinase or nik nck interacting kinase the mouse ortholog is a serine threonine s t kinase that belongs to the mammalian family of ste20 protein kinases due to their shared homology to the budding yeast kinase ste20p. Experimental evidence at protein level i. Homo sapiens human status. A summary of human ste20 related kinases is shown in fig.

This kinase has been shown to specifically activate mapk8 jnk. Entrez gene summary for map4k4 gene the protein encoded by this gene is a member of the serine threonine protein kinase family. Serine threonine kinase that may play a role in the response to environmental stress and cytokines such as tnf alpha.

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Map4k4 Wikipedia

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Map4k4 Info

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